Organic Cation Transporter Variation and Response to Smoking Cessation Therapies

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Organic cation transporter variation and response to smoking cessation therapies.

INTRODUCTION We evaluated chr6q25.3 organic cation transporter gene (SLC22A1, SLC22A2, SLC22A3) variation and response to smoking cessation therapies. The corresponding proteins are low-affinity transporters of choline, acetylcholine and monoamines, and smoking cessation pharmacotherapies expressed in multiple tissues. METHODS We selected 7 common polymorphisms for mega-regression analysis. W...

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ژورنال

عنوان ژورنال: Nicotine & Tobacco Research

سال: 2014

ISSN: 1462-2203,1469-994X

DOI: 10.1093/ntr/ntu161